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Saturday, January 23, 2016

UNILORIN 2014-2018 Faculty Of Pharmaceutical New B.Pharm Curriculum

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Dean’s Office
A. Agunu  B. Pharm. , M. Sc. , Ph. D. (ABU)  Professor &Ag. Dean
I. S. Bello  B. Pharm. , (ABU); M. Pharm. (Ibadan); Ph. D.
Lecturer I and Sub-Dean
R. S. Abegunde  HND, LL. B (Ilorin)  Faculty Officer
Department of Clinical Pharmacy and Pharmacy Practice
A. Giwa
B. Pharm. (ABU); MPA (Maiduguri); MPH
(Ilorin), M. Pharm. , Ph. D. (Lagos) Senior Lecturer & Ag. Head
I. Suleiman  B. Pharm. (ABU); M. Pharm. (Lagos); Ph. D.
Reader (Adjunct)
I. S. Bello  B. Pharm. (ABU); M. Pharm. (Ibadan); Ph. D.
Lecturer I
I. F. AbdulAzeez  B. Pharm. (ABU); M. Pharm. (Ibadan)  Lecturer II
F. E. Williams  B. Pharm. (Benin); MCOMM. H. ,   Lecturer II
M. O. Jamiu  B. Pharm. (ABU); Pharm. D. (Benin)  Lecturer II
H. B. F. Giwa  B. Pharm. (ABU); M. Pharm(Lagos)  Assistant Lecturer
F. O. Aliyu    B. Pharm. (Jos)    Assistant Lecturer
A. O.
B. Sc. (Ilorin); PGDM  Technologist II
A. Abdulraheem  B. Tech. (MAUTECH)  TechnologistII
Department of Pharmacognosy and Drug Development
A. Agunu  B. Pharm. , M. Sc. , Ph. D. (ABU)  Professor & Head
E. O. Ajaiyeoba  B. Sc, M. Sc. , Ph. D. (Ibadan)  Professor (Sabbatical )
B. A. Lawal  B. Pharm. (OAU); MSc (Ibadan)  Lecturer II
S. O. Usman  B. Pharm. , M. Sc. (Lagos)  Lecturer II
M. K. Salawu  B. Pharm. (ABU)  Assistant lecturer
A. Abdullah  B. Pharm. (Maiduguri)  Assistant lecturer
A. O. Olutayo  HND   Assistant Chief Technologist
A. O. Durotola  B. Sc. (UNAAB); M. Sc. (Ilorin)  Assistant Chief Technologist
Department of Pharmaceutical and Medicinal Chemistry
M. T. Bakare–Odunola B. Sc. (Maiduguri); M. Sc. , Ph. D. (ABU) Professor& Head
J. A. Kolawole  B. Pharm. (Benin); M. Sc. (Lagos); PhD (ABU)  Professor (Adjunct)
T. O. Idowu  B. Sc. (Ado-Ekiti), M. Sc. , Ph. D. (Ile-Ife)  Senior Lecturer
(Sabbatical )
S. T Abdullahi  B. Pharm. , M. Sc. (ABU)  Lecturer I
S. N Njinga  B. Sc. (Buea); M. Sc. , Ph. D (ABU)  Lecturer II
Q. Abdul-Ganiyu  B. Pharm. (Jos)  Assistant Lecturer
F. F. Abdulmajeed  B. Sc. (Ilorin); PGDE  Technologist II
K. S. Jubril  HND  Technologist II
Department of Pharmaceutics and Industrial Pharmacy
O. I. Aremu  B. Pharm. (OAU); M. Sc. (Ibadan); Ph. D.
Senior Lecturer & Ag. Head
T. A. Iranloye  B. Sc. , (OAU); M. Sc. (Iowa); Ph. D. (London)  Professor (Contract)
A. O. Shittu  B. Pharm. , M. Sc. , Ph. D. (ABU)  Senior Lecturer
A. T. Kola Mustapha  B. Sc. , B. Pharm. , M. Sc. , (Lagos); Ph. D.
Lecturer I
R. K. Animasawun  B. Pharm. (OOU)  Assistant Lecturer
J. B. Aina  Part I, II, C&G  Principal Technologist
Department of Pharmaceutical Microbiology and Biotechnology
A. O. Shittu  B. Pharm. , M. Sc. , Ph. D. (ABU)  Senior Lecturer& Ag Head
Y. K. E. Ibrahim  B. Sc. (ABU); M. Sc. , Ph. D. (Heideiberg)   Professor (Sabbatical )
S. M. David  B. Pharm. M. Sc. (ABU)  Lecturer II
H. Olufadi-Ahmed  B. Pharm. (ABU)  Assistant Lecturer
A. Abdulmalik  B. Pharm. (ABU)   Assistant lecturer
H. R. Bello  B. Tech. , M. Sc. (ATBU)   Principal Technologist
L. D. Olorukooba  B. Sc. (ABU)  Technologist II
O. Salami  B. Sc. (Al-Hikmah)  Technologist II
Department of Pharmacology and Toxicology
R. O. Ayanniyi  B. Pharm. (ABU); M. Sc. (Jos); Ph. D. (ABU)  Senior Lecturer & Coordinator
O. M. Kola-Olaniyan  B. Pharm. , M. Sc. (ABU).    Lecturer I
M. O. Amali  B. Pharm. (Jos); M. Sc. (OAU); Ph. D.
Lecturer II
H. Abdul-Ayodeji  B. Pharm. (ABU)  Assistant Lecturer
S. A. Atunwa  B. Pharm, (OAU)  Assistant Lecturer
A. I. Olapade  HND  Technologist II
B. Pharm.
100 Level
The following courses are to be taken as published in the Faculty of Life and Physical
CHM 101 (3), 115 (2), 112 (2), 132 (2), CSC 111 (2), PHY 191 (1), 115 (2), 125 (3), 142 (2),
152 (3), 192 (1), GNS 111 (2), 112 (2), PLB 101 (3), 108 (3), ZLY 106 (2), STA 121 (2), 124 (2)
= 39 Credits
PCP 101 is to be taken as published in the Department of Clinical Pharmacy and
Pharmacy Practice = 1 Credit
Department of Clinical Pharmacy and Pharmacy Practice
Course Description
PCP 101  Introduction to Pharmacy          1 Credit
Pharmacy in Ancient times (6000BC - 300AD), through the middle ages (600-1500 AD), to Modern times (1600-1950). History of Pharmacy in Nigeria from
pre-colonial to post independence era.  Pharmacy Education  and Curriculum
Development.  Pharmaceutical Associations in Nigeria.  Career prospects in
Pharmacy. Emerging trends in the Pharmacy Profession.
15 h(T); C
PCP 301 Pathology and Pathophysiology 2 Credits
Cell injury, tissue repair and wound healing. Cell growth and abnormal processes
in cell growth that relate to disease. Pathology of thrombo-embolic disorders.
Shock and associated pathologic processes. Genetic disorders. Immune disease
processes. Pathological processes due to infection and infestation. Pathology of
childhood disorders.
30 h (T); C, PR: PCL 203, 204
PCP 302 Introduction to Clinical Pharmacy    1 Credit
Definition,  scope  and function.  Hospital drug distribution systems,  medical
abbreviations,  terms  and terminologies.  Clinical interpretation of laboratory
values. General drug use in diarrhoea, constipation, nausea, vomiting and other
GIT disorders. Introduction to routinely used medical instruments /equipment.
15 h (T); C, PR: PCP 101, 301
PCP 304 Drug Information and Pharmacy Communication    1 Credit
Literature evaluation and drug information: methods and resources available for
the rapid and efficient handling of factual drug information; information storage;
retrieval and dissemination; resources needed for the establishment of a drug s
information centre; levels of drug information centre; functions and services of
various level; and drug information service. Pharmacists’ clinical role: dispensing
(in-and-out patients). organization of patient’s medical  charts  and medication
profiles;  medication dosages.  Monitoring  of drug interactions,  adverse drug
reaction detection, reporting and patient counselling. Types of communication:
appearance as a mode of communication; the various styles of listening / response
and applications to patient interview  and education.  Factors affecting patient
compliance with drug regimens. Pharmacist’s relationship with other health care
15 h (T); C, PR: GNS 111, PCP 101
PCP 306 Entrepreneurship: Theory and Practice 1 Credit
Definition, nature and functions and types of entrepreneurship. Managerial skills:
management process; importance of management in pharmacy business; industrial
pharmaceutical organization,  marketing,  advertising  and  sales  promotion.
Generating and developing business ideas. Conducting market surveys. Preparing
a business plan. Selecting a business locations. Policy and Legal Framework:
Legal procedure; information service; intellectual property rights; and patenting
of inventions. Starting and managing a Pharmacy enterprise: Pharmacy financing
and administration and drug supply management. Finance and Record Keeping:
Financing a business venture; costing and pricing products/services; financial
statements and their analysis, budgeting and cash flow. 
15h (T); C, PR: PCP 101
PCP 401  Pharmacotherapeutics I  2 Credits
Definition,  aetiology,  pathophysiology,  signs  and  symptoms,  prevalence,
diagnosis,  risk factors,  precipitating factors,  classification  and complications.
General principles of management.  Prognosis. Drug  interactions.  Patient
counselling.  Education  and  specific concept regarding  the following:
cardiovascular  and respiratory disorders  and   infections.  Over view of renal
function  and diseases:  chronic renal failure,  acute renal failure,  nephrotic
syndrome. Nutritional disorders.
30 h (T); C, PR: PCP 302, PCL 302, 304
PCP 403   Pharmacy Jurisprudence, Regulation &Control     1 Credit
General Laws of contract  and  Laws concerning employees/employers
relationship. Pharmacists Council of Nigeria under the Poison and Pharmacy Act:
Dangerous Drug s Act, Cap 48, 1960; Poisons and Pharmacy Act, Cap 152, 1960;
The Twelve Pharmacy Decrees under Military Rule. Drug  manufacture  and
advertisement. Sales of food, drug s, cosmetics and devices under the Food and
Drug s Administration (FDA). Dangerous drug s: medicinal dangerous drug s,
trade in dangerous drug s, power to control dangerous drug s in Nigeria and the
decree on Indian hemp. General principles of professional ethics. General laws of
professional liability. Decrees: food and drug ; National Agency for Food and
Drug Administration and Control (NAFDAC); National Drug Law Enforcement
Agency (NDLEA); fake drug s and unwholesome foods, essential drug lists.
Pharmacy regulation  and control:  definition;  regulatory authorities ;  various
aspects of regulatory pharmacy;  quality control /quality assurance;  clinical
evaluation; Current Good Manufacturing Practice (CGMP); Registration  and
15h (T); C, PR: PCP 101
PCP 405 Pharmacokinetics       2 Credits
Introduction: Drug  administration,  fate  and  influence of the route of
administration on bioavailability. Biological membranes, membrane models and
-partition principles. Physicochemical properties and pharmaceutical factors
affecting the processes of absorption, distribution, metabolism and excretion of
drug s.  Enzymology  and bioenergetics. Drug  receptors.  Bioavailability  and
bioequivalence: Drug  clearance,  hepatic elimination of drug s,  non-linear
pharmacokinetics,  relationship between pharmacokinetics parameters  and
pharmacologic response,  pharmacokinetic  profiles.  Application  of basic
principles of clinical pharmacokinetics.
15h (T), 45h(P); C, PR: PCL 301, PCP 302.
PCP 402   Pharmacy Management             2 Credits
Concepts of Management; Time management. Personnel management. Staffing
and recording system. Fiscal management: cash flow; income; profit and Loss
statement; Planning and managing  and establishing a cash flow budget. Tax and
Pharmacy business. Credit Management. Depreciation. Interest and inflation.
Financial analysis. Purchasing. Pharmaceutical marketing. Pharmacy computer
30h(T); C, PR:  PCP 306.
PCP 404  Pharmacotherapeutics II        2 Credits
Definition,  aetiology,  pathophysiology,  signs  and  symptoms,  prevalence,
diagnosis, risk factors, precipitating factors, classification, complications,  drug
interactions,  patient counselling.    Education  and specific concept regarding
following conditions: Endocrine and gastrointestinal disorders, hepatic, Joint and
connective tissue  and cutaneous diseases.  Infectious diseases:  cerebrospinal
meningitis and parasitic diseases.
30 h (T); C, PR: PCP 302, PCL 303, 304
PCP 406   Clinical Pharmacokinetics     2 Credits
Therapeutic drug monitoring (TDM) concept: Definition and clinical advantages
of TDM,    specific dosage prescribing requirements/guidelines under certain
conditions, prescribing for the pediatric and elderly populations, prescribing for
renal and liver impaired patients, prescribing pregnant and lactating mothers,
pharmacokinetics in disease states modify body perfusion, pharmacokinetics in
disease  state modifying protein binding,  consideration of the clinical
pharmacokinetics of selected drug s used in various disease state. Applications of
clinical pharmacokinetic parameters
15h(T), 45h(P); C, PR: PCL 301, PCP 302. 
PCP 501  Public Pharmaceutical Healthcare          2 Credits
Hospital pharmacy:  Types  and definition of hospital  and their  organization/
administration,  outpatient  and  inpatient pharmacist’s responsibilities  and
management of hospital pharmacy. Community Pharmacy: Scope, establishment,
importance  and  function of  community Pharmacy.  Essential Drug Policy:
National Essential Drug Programme,  National Drug Formulary,  National
Essential Drug List, Drug Revolving Fund  Scheme, Drug Distribution, Drug
Law,  National Drug Policy,  National Health Policy.  Roles of the clinical
pharmacist in National Health Policy, Healthcare Financing and National Health
Insurance Scheme. Clinical Pharmacists in Primary healthcare: Definition and
components of primary healthcare,  immunization campaign  and  routine
immunization schedule,  vaccine management  and Cold chain management.
HIV/AIDs prevention  care,  management  and support.  Antiretroviral  therapy.
Principles  of antimicrobial therapy  and antibiotic policy.  Family planning,
contraceptive techniques and oral contraceptives. Women’s Health. Roll back
malaria programme.
30h (T); C, PR: PCP 304, 306.
PCP 503 Pharmacotherapeutics III      2 Credits
Definition,  aetiology,  pathophysiology,  signs  and  symptoms,  prevalence,
diagnosis,  risk factors,  precipitating factors,  classification  and complications.
General principles of management:  prognosis, drug  interactions,  patient
counselling. Overview of mental illness. Overview of diagnostic method criteria.
Schizophrenia education and specific concept regarding affective and neurological
30 h (T); C, PR: PCP 401, 404.
PCP 505Research Methodology & Statistics         2 Credits
Research Proposal Writing,  Sample size determination,  sampling techniques,
biomedical writing and journal critique. Review of basic statistics from measures
of central tendency to paired sample hypothesis; parametric and non-parametric
analysis, multi-sample hypotheses and multiple comparisons, Chi-square analysis,
Student’s t- test,  analysis of variance, analysis of variance (ANOVA); simple
linear and multiple regression; comparing linear regression equations.  Binomial
distribution, testing for randomness; Pearson correlation. Analyzing data using
statistical computer packages.
30 h (T); C
PCP 502  Contemporary Concepts in Pharmacy Practice I    2 Credits
Pharmaco-Economics: Economics as a tool for making choices; basic economic
concepts;  economics of the public sector;  goals of public expenditure.  The
financing of public expenditure.  Distribution  issues  and the use of subsidies.
Understanding the private sector. Market and competition. Ethics and business.
Government interaction with the private sector. Health policy in conditions of
poverty. Overview of pharmaco-economics methodologies. Health related quality
of life (HRQL) in phamaco-economics. Clinical trials in pharmaco-economics.
Application of pharmaco-economics in health care delivery systems.
Pharmaceutical care: Definition, evolution, philosophy, practice principles, drug
related problems,  steps in providing pharmaceutical care,  documenting
pharmaceutical care and barriers to pharmaceutical care. Models of pharmaceutical
30 h (T); C, PR: PCP 401, 404
PCP 504 Ethical Dispensing Practical    2 Credits
Utilization of patient medical records. Development of communication skills with
patients  and physicians.  Prescriptions  and signed orders:  legal requirements,
endorsement  and retention of prescriptions  and signed orders,  record keeping
books and common prescription practices. Incompatibilities challenges/solutions in
product  formulations  and  Prescriptions.  Pharmacist-patient  and  pharmacistphysician interactions. Handling of typical hospital prescriptions and dispensing of
such in the laboratory.  Posting of students to nearby hospitals/clinics  and
community pharmacies for acquisition of experience.
90(P); C, PR: PCT 303, 304, 401.
PCP 506 Clinical Ward Round and Clerkship in General Medicine  4 Credits
Clinical Ward Round: attachment to medical wards for six (6) rotations; drug
therapy monitoring; attachment to a patient per ward and presentation of clinical
cases; utilizing the SOAP and CORE-PRIME-FARM approach and submission of
written report in compliance with given outline. Clinical Clerkship: knowledge of,
and intimate involvement with all specialized clinics in the hospital, especially
University of Ilorin Teaching Hospital (U. I. T. H. ). An oral case presentation and
a written report submitted at the end of each rotation.
90h Clinical Ward round, 45h Clinical Clerkship, 45h Presentations; C, PR: PCP 401, 404
PHP 599Project.                   4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission of
a project.
180h (P); C
Department of Pharmacognosy and Drug Development
Course Description
PCG 201  Introductory Pharmacognosy, Microscopy and Cytology    3 Credits
Pharmacognosy; Definition of terms. Classification, collection, preparation and
evaluation of crude drug s.  Microscopy:  Principles,  types,  use  and care of
microscopes;  microscopical  techniques  and  preparations;  modified light
microscopy;  quantitative microscopy.  Photomicrography. ;  importance of
microscopes. Cytology, Cytomorphology and Cytogenesis.
30h (T), 45 h (P); C
PCG 202  Vegetable Drug s, and Taxonomy 3 Credits
Introduction. Drug s in the following morphological groups: Morphological
Groups: woods e. gQuassia; bark (Cinchona, Cascara and Cassia) ; Leaves,
(Stramonium,  Senna,  Digitalis,  Tobacco,  Cannabis); flowers,  (Pyrethrum  and
Clove); Fruits,  e.  g  Capsicum,  Fennel,  Cardamum; Seeds,  e.  gStrophanthus,
Calabar bean, Castor and Roots, Rauwolfia, Ginger, Ipecacuanha.
30 h (T), 45 h (P); C
PCG 301  Fibres , Extraction and Separative Techniques      2 credits
Fibres: Introduction; importance, relevance, uses and classification of various
fibres; production, diagnostic character and general properties. Standardization
and evaluation of surgical products and dressings. Extraction: Introduction and
processes used in the preparation of galenicalsin pharmacy and official methods
of extraction of crude drug s. Separative techniques: column chromatography,
paper chromatography;  thin layer chromatography;  gel filtration  and
electrophoresis. .
15 h (T), 45 h (P); C, PR: PCG 201, 202
PCG 302  Photochemistry of Carbohydrates, glycosides, tannins, proteins and enzymes. 2 credits
Definition, scope, classification of plant metabolites. Importance of primary and
secondary metabolites.  Nature  and properties of various plant constituents.
Phytochemistry.  Carbohydrates,  Glycosides,  Tannins,  Resins,  Enzymes  and
Enzyme-containing drug s.
15h (T), 45 h (P); C, PR: PCG201, 202
PCG 304  Phytochemistry of Alkaloids, Terpenes and Volatile oils    2 credits
Theory on  Phytochemistry of alkaloids,  terpenes.  volatile  oils.
Characterization and identification of alkaloids, terpenes and volatile oils
15 h (T), 45h (P); C, PR: PCG 201, 202
PCG 401  Advances in Phytochemistry, Chromatography and Development of
New Drug       3 Credits
Advances in phytochemistry:  study of chemistry,  pharmacology,  uses  and
occurrence in plants of antineoplastics,  cardiovascular drug s,  anti-malarial,
steroids  and steroidal hormones.  Plant pigments  and plant growth substances.
Sugar substitutes of plant origin.  Development of new drug s from plants.
Screening  and evaluating new plant constituents.  Methods  and technology of
developing new formulations. Advanced chromtographic processes: application of
paper chromatography; ion-exchange chromatography; gas chromatrography; high
pressure liquid chromatography.
30 h (T), 45 h (P); C, PR: PCG 301, 302
PCG 402  Research Methods and Plant Tissue Culture Techniques    3 Credits
Research Methods:    Importance of medicinal plants research;  methods  and
techniques applied to  research on plant materials;  selection,  identification,
collection  and preparation of the plant materials.  Extraction,  isolation  and
analysis of the active phytochemicals  and  their characterization  and
identification. Plant tissue culture in the production of pharmaceuticals through
biotechnology. Introduction, equipment and facilities require for tissue culture
work; factors affecting growth of cultures, applications of plant tissue culture and
secondary plant products.  Origin  and biogenesis of natural drug products:
definition,  importance of metabolism  and metabolic path-ways  and types of
biochemical reactions.
30h (T), 45h (P); C, PR: PCG 301, 302.
PCG 501 Nigerian Medicinal and Ordeal plants, Forensic Pharmacognosy,
Traditional Medicine and Evaluation of Crude Drug s       3 Credits.
Nigerian Medicinal and Ordeal Plants: classification and study of representative
and their groups; Forensic pharmacognosy: Legal control; Toxicological analysis
and Classification of poisons. Traditional Medicine: Introduction; Methods of
preparation and quality control of traditional medicinal products e. g.  Plant and
animal products used in traditional medicines. Evaluation and standardization of
crude  drug  s:  Introduction;  Definitions  and  implications of evaluation;
Determination of moisture content in drug s and chemicals
30 h (T), 45h (P); C, PR: PCG 401, 402
PCG 502  Herbal medicine, Chemotaxonomy, Genetics and Plant Ecology 3 Credits
Herbal medicine;  selection;  dose  and remedies.  Pesticides  and Herbicides;
Genetics in pharmacognosy. Chemotaxonomy and comparative phytochemistry.
30 h (T), 45h (P); C, PR: PCG 401, 402
PHP 599 Project            4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission a
180h (P); C
Department of Pharmaceutical and Medicinal Chemistry
Course Description
PCH 201 Pharmaceutical Inorganic Chemistry        1 Credit
Hydrogen  and its compounds.  Group properties of elements.  Pharmaceutical
applications of the Groups I to VIII elements.  Transition elements  and their
pharmaceutical applications.  General gastrointestinal agents.  Coordination
compounds. Complexes and chelating agents.
15h (T); C
PCH 203  Pharmaceutical Organic Chemistry        2 Credits
General classes of Organic Compounds,  structural concepts,  nomenclature,
occurrence, reactions, infra-red spectroscopy, physical and chemical properties
with examples of some pharmaceutical agents of the following groups: alkenes,
alkynes,  aromatic  and fused aromatic hydrocarbon; halogenated hydrocarbons;
alcohols and phenols; aldehydes and ketones; carboxylic acids, esters, lactones,
amides, anhydrides and halides; amines, amides, Imides, carbamates derivatives,
nitro and nitroso compounds.
15 h (T), 45h (P); C, PR: CHM 101, 112
PCH 202  Pharmaceutical Analytical Inorganic Chemistry      3 Credits
Preliminary analysis of acids and basic radicals. Preparation of solutions of salts.
General scheme for the separation of cations into groups. Reactions of cations and
anions. qualitative examination of anions and cations of groups I- VII.
30h(T), 45h(P); C
PCH 204   Pharmaceutical Physical Chemistry        2 Credits
Colligative properties. conductivity of solutions. Theory of electrolytes. Buffer
solutions. Solubility. Thermochemistry: Chemical equilibrium and chemical
kinetics, basic thermodynamics, thermochemical formulae and laws.
30h (T), C
PCH 205  Introduction to Physical Biochemistry          2 Credits
Water, physical properties, hydrogen binding, water as solvent, solution, acids,
and bases.    P
,  PKa values  and their effects on cellular activities,  buffers.
Structure of cells, cell-organelles, cell types, integration of cellular functions,
division and differentiations.
30 h (T); R
PCH 206    Structure  and  Chemistry of Biomolecules  and  Biosynthesis  of
Macromolecule      2 Credits
Chemistry of amino-acids, proteins, carbohydrates, lipids, enzymes, vitamins and
co-enzymes.  Structures  and  functions of macromolecules:  polysaccharides,
glycoproteins, nucleic acids, lipids, dextrans, ascorbic acids.
30 h (T); R
PCH 207 Metabolism of Biomolecules 2 Credits
Degradation of carbohydrates:  sugar,  glucose,  reactions of sugar,  glycolysis,
tricarboxylic  acid cycle.  Classification of lipids,  oxidation of fats,  ketones,
cholesterol.  Oxidative degradation of amino-acids,  urea cycle creatinine  and
creatinine metabolism.
30 h (T); R
PCH 301   Pharmaceutical Analysis I   2 Credits
Acid Base titrations: aqueous and non-aqueous acid-base titrations. Oxidationreduction titrations. Complex metric titrations. Gravimetric analysis. Gasometric
15h (T), 45h (P); C, PR: PCH 201
PCH 303  Pharmaceutical Organic Chemistry I 2 Credits
Heterocyclic compounds.  Medicinal Chemistry of Natural Products: steroids,
alkaloids, flavonoids and their structural activity relationship. Stereochemistry:
geometric isomerism, molecular asymmetry and chirality. Optical isomerism:
optical activity, conformation of open-chain and ring systems.
15h (T), 45h (P); C
PCH 302   Pharmaceutical Organic Chemistry II        3 Credits
Introduction to organic reaction mechanisms: mechanisms of reactions, aliphatic
and aromatic nucleophilic substitution,  aliphatic  and aromatic electrophilic
substitution and eliminations. Introduction to addition reactions:  carbon-carbon
multiple bonds, conjugated diens, other conjugated systems and carbon-hetero
multiple bonds. Rearrangement reactions. Reduction and oxidation.
30h (T), 45h (P); C, PR: PCH 203
PCH 40l Pharmaceutical Analysis II          3 Credits
Absorption spectrophotometry. Colorimetry. Infrared spectroscopy. Fluorometry.
Atomic absorption spectroscopy.  High performance liquid chromatography.
Gaschromatography  Mass spectrometry.  Nuclear magnetic  resonance.
Potentiometry. Polarimetry. Polarography and amperometry.
30h (T), 45h (P); C, PR: PCH 301.
PCH 403 Physicochemical Principles of Medicinal Chemistry     2 Credits
Influence of physico-chemical properties  of drug s  on biological activity.  Ferguson
principles. Drug s and receptors. Theories of drug action. Mechanisms of drug action.
Pharmacokinetics  and bioavailability.  Protein binding of drug s.  Pharmacodynamics.
Procedures followed in drug design  including bioisosterism  approach.  Quantitative
Structural activity relationship.
30h (T); C, PR: PCH 302
PCH 402 Analytical Quality Control  2 Credits
Introduction to the problems of drug quality control. Official methods of drug analysis
with examples. Analytical methods used by manufacturers with examples. Importance of
standards in drug quality control, use and storage. Impurities in pharmaceuticals and
their sources. Limit Tests. Different methods of analysis of some groups of drug s in
common use in Nigeria (analgesics, antibiotics, antihelminthics and amoebicides).
15h (T), 45h (P); C, PR: PCH 301
PCH 501  Medicinal Chemistry I  2 Credits
Nomenclature, physical and chemical properties, uses and mechanisms of action,
synthesis and structural activity relationship. Assay and metabolism of the following
classes of drug s: Analgesics and antipyretics; local and general anaesthetics; sedative
and  hypnotic;  anticonvulsants.  Adrenergics  and  cholinergics;  antihistamines;
hypoglycaemics, antihypertensives and diuretics.
30h(T); C, PR: PCH 401, 403
PCH 503  Medicinal Chemistry II        2 Credits
Nomenclatures, physical and chemical properties, uses and mechanism of action,
synthesis  and structural activity relationship,  assay  and metabolism of the
following classes of drug s: sulphonamides and sulfones, antibiotics, antimalarials,
amoebicides,  trypanocides  and  antihelminitics,  antineoplastics,  antivirals,
gastrointestinal agents, vitamin, steroids and steroid hormones.
15h(T); C, PR: PCH 403
PCH 502  Chemical Aspects of Drug Metabolism         1 Credit
Phase I reactions and general pathway of metabolites. Metabolism of pesticides
and other chemicals. Metabolism of steroids and sterols. Enzyme induction and
stimulation.  Phase II reactions.  Factors affecting metabolism.  Relationship  of
phase I  and phase II reactions.  Metabolic schemes of some selected drug s.
Stereochemical aspects of drug metabolism: substrate and product stereochemistry
and substrate-product selectivity. Biochemical aspects of drug metabolism. Drug
metabolizing enzymes. Enzymes operative in phase I reactions. Pharmacogenetics.
15h (T); C, PR: PCH 403
PCH 504 Radiopharmaceuticals and Contrast Media 1 Credit
Definition of terms, properties of radiation and radioactive decay, production of radionuclide, stability and storage, radiation hygiene. Quality control of radiopharmaceutical.
Applications of radiopharmaceuticals. Radiopaque contrast media.
15h (T); C
PHP 599 Project            4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission a
180h (P); C
Department of Pharmaceutics and Industrial Pharmacy
Course Description
PCT 201 Pharmaceutical Calculations          1 Credit
Units of weights and measures. Inter-conversions of weights and measurements.
Units. Abbreviations. Simple calculations. Various dosage calculations:  pediatric,
geriatric, mean generation times, decay and potency calculation. Kinetic equations
and rates of reactions.  Solubility:  iso-osmotic solutions,  milliequivalents  and
millimoles.  Calculations involving  use of prefabricated dosage forms in
compounding procedures.
15 h (T); C
PCT 202  Physical Pharmacy          1 Credit
Phase equilibria  and  phaserules.  Colllioids.  Stability of colloidal  systems.
Lyophobic and lyophilic. Solutions. Surface science, optical and kinetic properties
of colloids. Electrical, rheology and viscosity properties of colloids.
15h (T); C
PCT 204 Technology of Formulation             2 Credits
Properties of Solid Systems: Particles size analysis and separation, size reduction;
mixing. Properties of liquid systems. Extraction: solid/liquid separation (filtration
and centrifugation). Heat transfer; evaporation and distillation.
30h (T); C
PCT 206 Introduction to Dispensing             1 Credit
Unit operations e. g. size reduction. Particle size determination, mixing of solids in
semi-solids,  preparation of simple solutions,  mixtures,  powders etc.    drying,
filtration. extraction. distillation. centrifugation. Aromatic waters and dissolution
45h (P); C
PCT 30l Technology of Liquid and Semi-solid Formulations     2 Credits
Liquid Formulations: solutions, mixtures, colloids, liniments, lotion and paints.
Labeling and packaging. Emulsions and suspensions: definitions, characteristics of
pharmaceutical suspensions and methods of formulation. Semi-solid formulations:
formulation; preparation, packaging and storage of suppositories and pessaries.
Ointments. creams, pastes and aerosol formulations.
30h (T); C, PR: PCT 204
PCT 303  Theory of Dispensing       1 Credit
Definitions  and terminologies.  Components of a prescription.  Latin  and other
standard abbreviations.  Common expressions.  Weighing  and  measurement
instruments/tools. Accuracy of weights and measurements. Uniformity of doses.
Drug and pharmacy information books. Labelling of dispensed medicinal products.
Auxiliary labels. Basic techniques used in the formulation of extemporaneous
products.  Basic dispensing procedures for different dosage forms. Drug
classifications (poisons, dangerous drug s, etc), handling and disposal.
15h (T); C, PR: PCT 201
PCT 302  Technology of Solid Formulations           2 Credits
Solid Formulation: Powders and oral preparations, single and compound powders.
Topical preparations:  Bulk powders,  dusting powders,  medical  surgical,
standardized powders. Incompatibilities in powders. Hard gelatin and soft elastic
capsules; granules and tablets; technology of coating. Prolonged action tablets.
Tablets quality control tests.
30h (T); C, PR: PCT 204.
PCT 314  Dispensing Practical      1 Credit
Use of basic dispensing instruments and tools (balances, mortars, homogenisers,
measuring apparatus). Preparation of different dosage forms( powders, solutions,
mixtures,  emulsions,  ointments,    liniments,  eye/ear drops,  capsules,  granules,
coated and uncoated tablets etc) and tackling incompatibilities.
45 h (P); C, PR: PCT 206
PCT 411  Formulation of Dosage Forms    1 Credit
Formulation  and evaluation of emulsion.  Stabilitystudies e.  g.  creaming  and
cracking. Evaluation of calamine lotion. Studies on derived properties of powder.
Evaluation of suspension. Evaluation of capsules. Formulation and preparation of
injections. Single dose and Multidose.
45h (P); C, PR: PCT 304
PCT 402 Quality Control and Stability of Pharmaceutical Preparations   3 Credits
Definitions: quality Control, quality assurance and manufacturing practice. Quality
assurance. Stages in production of a new drug . Quality control of premises.
Environment  and  raw materials.  In-process quality control.  Stability of
pharmaceuticals:  Kinetics,  mechanism of degradation,  physical stability  and
evaluation of microbial contamination of pharmaceutical preparations.
30 h (T), 45 h (P); C, PR: PCT 202,  205, 304
PCT 403  Formulation Technology and Water Production      1 Credit
Advanced Formulation Technology. Recent advances in solid dosage. Formulation
technology.  Microencapsulation as a technique of formulation.  Dispersion
technique. Transfusion fluid technology. Water Production: Purified water; water
for injection and pyrogenic water. Still design. Vapour compression still.
15h (T); C, PR: PCT 301, 302
PCT 404  Radiopharmaceuticals and Medicinal Gases      1 Credit
Diagnostic application of  isotopes.  Preparation of radiopharmaceuticals.
Radiopharmaceuticals used in medicine.  Medicinal  and pharmaceutical gases.
Contaminants and container markings. Pressure reducing regulators. Storage of
15 h (T); C
PCT 501 Industrial Pharmacy and Biopharmaceutics      2 Credits
General requirements, production management, Pilot. Plant scale up techniques.
Solid  and semi-solid dosage forms.  Sustained released dosage Forms.  Sterile
dosage forms.  Biopharmaceutics:  factors affecting absorption of  drug  s;
formulation factors affecting biological performance of drug s. determination of
in-vitro dissolution rates and in vivo correlations; bioavailability and estimation of
drug s availability by observed pharmacological effects.
30 h (T); C
PCT 502  Product Development and Good Manufacturing Practice 2 Credits
General inspection. Quality assurance and quality control procedures and sampling. Personnel
and training. Environmental hygiene. Equipment planning procedures. Production
formula and manufacturing instructions. Handling of starting materials. Labeling
instructions. Control of packaging materials and packing operations. Supervision
of production. Storage, transport and distributions. Manufacture and control of
sterile medicine products. Premises processing.
30h (T); C, PR: PCT 402
PCT 503 Industrial Pharmacy 1 Credit
Visitation to Pharmaceutical Companies to familiarization with methods and
machineries used for pharmaceutical preparations. Preparation and evaluation of
cosmetics.  Tablet production by direct compression  and Slugging  and wet
granulation methods. Evaluation of tablets.
45 h (P), C, PR: PCT 401.
PHP 599 Project.             4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission a
180h (P); C
Department of Pharmaceutical Microbiology and Biotechnology
Course Description

PMB 201  Introduction to Pharmaceutical Microbiology         3 Credits
Historical background and relevance to the practice of Pharmacy. Classification of
living forms.  General microbial  cell structures  and functions.  Classification of
bacteria  and  their characterization.  Nutritional  and  growth requirements.
Enumeration of microorganisms.  Microbial products.  Properties of  selected
pathogenic  organisms.  Microscopic studies.  Bacterial culture media.  Fungi.
Rickettsiae. Viruses and their importance in pharmacy and medicine. Protozoa of
public health importance.
30h (T), 45(P); C
PMB 202 Chemical Antimicrobial Agents and Disinfections       3 Credits
Chemical antimicrobial agents: types and properties and mechanism of action. Ideal
properties of chemical disinfectants.  Factors affecting activity of chemical
antimicrobial agents.  Methods of evaluation of the antimicrobial properties of
chemical disinfectants.
30h (T), 45h (P); C
PMB 301 Principles and applications of Biotechnology      2 credit
Introduction to biopharmaceuticals. Biotechnology manufacturing. Facilities and
environmental biotechnology. Biotechnology products in current use.
30h (T); C, PR: PMB 201
PMB 303P harmaceutical Aspect of Immunology        2 Credits  
Immunology:  Infection,  basic molecular biology,  bacteria toxin,  invasive pathogens,
antigens  and antibodies.  Immunological products: vaccines  (viral vaccine.  Rickettsia
vaccine  etc),  toxoids.  Antisera (Diphtheria)  and  diagnostic agents.  Immunization
schedule. Production and preservation of antibodies, sera and vaccines.
30h (T); C, PR: PMB 201
PMB 312 Biological Products    1 Credit
Blood:  Plasma  and Plasma substitutes.  Blood fractions.  Red  cell antigen  and
importance of blood transfusion. ; Sutures and ligatures: manufacture, sterilization
and uses.
15 h (T); C
PMB 314 Sterilization and Aseptic Processes, Sterile Products     3 Credits
Microbial death. kinetics of cell death. Sterilization processes: moist and dry heat
sterilizations, irradiation, sterilization by filtration. Principles of aseptic techniques
and aseptic processing.  Sterile preparations:  formulation  and preparation of
injections,  eye preparations  and powders.  Aseptic techniques  and processes.
Solvents for parenteral preparations; water for injection.  Pyrogens; isotonicity.
Sterility testing: design and operation
30h (T), 45h (P); C, PR: PMB 202, 303
PMB 411 Pharmaceutical and Veterinary Parasitology       1 Credit
Epidemiology:  principles  and  indices,  epidemiology of infectious  and  noninfectious diseases in animals,  microbial diseases of domestic animals  and
antimicrobial agents used in their management.
15h (T); C
PMB 403 Preservation of Pharmaceutical Products      1 Credit
Microbial contamination of pharmaceuticals;  effects on products  and users.
Preservatives  and  evaluation of  their preservative effectiveness.  In-process
microbiological control procedures.
15h (T); C, PR: PMB 304.
PMB 412 Chemotherapeutic Agents, Drug Resistance and Bacterial Genetics  3 Credits
Historical development of antibiotics:  antibacterial,  antifungal,  antiviral  and antituberculosis agents. Factors affecting anti-microbial activity. Therapy approaches in
infection management. Factors affecting choice of therapies. Drug Resistance: Patterns
of genetic bases for bacterial resistance; Plasmids and other resistance transfer factors.
Production of penicillinase and importance of resistance transfer factors.
30h (T), 45h (P); C, PR: PMB 301, 303.
PMB 414 Production and Marketing of Biotechnology Products      2 credits
Production of biopharmaceuticals and process validation, Business in biopharmaceuticals
and intellectual property.
15 h (T), 45 (P); C, PR: PMB 301
PMB 511 Analytical Microbiology and Fermentation Technology   3 Credits
Analytical Microbiology:  evaluation of antibiotic activity,  assay procedures,
screening/testing the antimicrobial activity of different chemicals, plant extracts,
bacterial and fungal products. Fermentation technology: fundamentals of industrial
fermentation, genetic/enzymatic engineering techniques, production of antibiotics;
production of vitamins,  alcohols,  acetone,  microbial food.  Microbiological
transformation of steroid.
30h (T), 45 (P); C, PR: PMB 402
PMB 502 Pharmaceutical Biotechnology      1 Credit
Nucleic Acids: Replication and transcription. Control of gene expression. DNA
damage  and repair;  Basic techniques in biotechnology.  Medically important
recombinant proteins. Production of medically important polypeptides. Engineering
antibodies for therapy. Biotechnology in vaccine development. New diagnostics.
Use of recombinant DNA and antibody technology.
15h (T); C, PR: PMB 401, 402
PHP 599 Project.                   4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission of a
180h (P); C
Department of Pharmacology and Toxicology
Course Description
PCL 201     Anatomy of Essential Organs        2 Credits
Cardiovascular System:  brief heart  and vascular free with blood vessels,
structures of heart and blood vessel. Respiratory system: gross anatomy of the
thorax, nasal cavity, trachea, lungs and bronchioles diaphragm and respiratory
movement. Gastro-intestinal tract: organs of the lower and upper gastro-intestinal
wall. Renal system: urogenital system, microscopic anatomy of the urogenital
organ, pelvic endocrine organs
30 h (T); R
PCL 202    General Embryology and Respiratory System 2 Credits
Reproduction:  male and female reproductive organs. Brain and the Spinal cord:
histology, structures of, and composition of central nervous system. Sense organs:
histology, structures of the eyes, ear, skin
30 h (T); R
PCL 203 Physiology of Essential Organs          3 Credits
Cardiovascular system blood composition. Body fluids. Heart and blood vessels.   Regulatory
System:  lungs,  bronchioles  and gaseous exchange.  Gastro-intestinal tract  :
alimentary canals,  secretion  and motility.  Renal System:  kidney  and urine
formation. Reproductive System: Male and female organs, hormones.
45h (T); R
PCL 204 Physiology of Nervous System    2 Credits
Central nervous system: brain, spinal cord and pathways, cortical and cerebral
control of motor.  Muscle movement:  basal ganglia reticular activity system.
Autonomic Nervous System . Structure and functional outflow of nerves from
CNS:  Sympathetic;  Parasympathetic.  Neurotransmitters:  noradrenaline,
acetylcholine.  Somatic nervous system,  neuromuscular transmission  and
30 h (T); R
PCL 301 Introduction to Pharmacology  2 Credit
Definition of pharmacology  and its subject coverage,  Factors modifying drug
action; Routes of drug administration  and their characteristics;  Introduction to
pharmacokinetic Processes,  Introduction to Pharmacodynamics, Dose-response
relationships, Drug toxicity, Introduction to drug screening and evaluation.
15h (T), 45 (P); C, PR: PCL 201, 202, 203, 204, PCH 205, 206, 207
PCL 303  Pharmacology of the Autonomic Nervous System and Neuromuscular
Junction  2 Credits
Introduction:  Anatomical  and physiological links of the autonomous nervous
system with Central Nervous System  (CNS).  Cholinergic system\  adrenergic
system. Ganglion stimulants and blockers; Neuromuscular junction blockers.
15h (T), 45h (P); C, PR: PCL 201, 202, 203, 204, PCH 205, 206, 207
PCL 302  Systemic Pharmacology I: Cardiovascular System      2 Credits
Cardiac glycosides.  Antihypertensive agents.  Antihypotensive agents.
Antiarrhythmic agents. Coronary vasodilators. Hypolipidemic drug s. Diuretics
and Antidiuretics.
15h (T), 45h (P); C, PR: PCL 201, 202, 203, 204, PCH 205, 206, 207
PCL 304  Systemic Pharmacology II          2 Credits
Drug s used in the treatment of:  Respiratory system  (asthma  and cough)
Gastrointestinal system (peptic ulcer, diarrhoe),  Blood (anaemias, anticoagulants,
fibrinolytics agents)  and Autocoids  ( histamine  and antihistamine,  antagonist,
prostaglandins) diseases.
30h (T), C; PR: PCL 201, 202, 203, 204, PCH 205, 206, 207
PCL 401  Pharmacology of the Central Nervous System. 3 Credits
Introduction. Aliphatic Alcohols, Narcotic Analgesic. Non-narcotic analgesics.
Drug s used in the treatment of gout, Antitussives. General anaesthetics, local
anaesthetics. CNS Stimulants and Analeptic. Anticonvulsants. Centrally acting
muscle Relaxant. Psychotropic drug s.
30 h (T), 45 h (P); C, PR: PCL 301
PCL 402 Chemotherapy of Neoplastic Diseases 1 Credit
General Introduction: Nucleic acid metabolism, protein synthesis, cell division.
Chemotherapy of cancer.
15h (T); C, PR: PCL 301
PCL 403 Chemotherapy of Parasitic Bacterial, Fungal and Viral Diseases 2 Credits
Introduction.  Malaria.  Bacterial sensitivity  and  resistance.  Classification  and
mechanism of action of antimicrobial drug s. Antibacterial Agents. Antifungal
Agents.  Antiviral Agents.  Treatment of Mixed infections  and  antibiotic
prophylaxis.  Amoebiasis.  Trypanosomiasis.  Leishmaniasis  and  toxoplasmosis.
Fluke infestations. Fascioliasis. Tapeworm infestations. Roundworm infestations.
30 h (T); C, PR: PCL301
PCL 404   Endocrine Pharmacology    2 Credits
Antithyroid Drug s and Inhibitors: Adreno Corticortical Tropic Hormone (ACTH)
and Adrenocortical steroids: insulin and antidiabetic agents, Pharmacology of the
reproductive system, drug s used in obstetrics and gynaecological disorders.
15h (T), 45h (P); C, PR: PCL 301.
PCL 405  Immuno-Pharmacology           1 Credit
Introduction:  Overview of the Immune System.  Inflammation  and  the
Cardiovascular System: Inflammation in the muscle, skeletal and respiratory
system. Pathological and therapeutic modulation of the immune system.
15h (T); C, PR: PCL301
PCL 501 Toxicology    3 Credits
Introduction, definition and scope, pesticides, insecticides, herbicides, rodenticides,
fungicides  and  fumigants,  Solvent,  vapours  and  gases,  food toxicology,
phytotoxicity,  toxins of  animal origin: toxicology of cosmetics: social poisons
(Drug Abuse), radiation and radioactive materials. Heavy metal poisoning, heavy
metal antagonists, industrial poisons, environmental toxicology, hazardous / toxic
30 h (T), 45h (P); C, PR: PCL 304, 401.
PCL 502 Molecular Pharmacology        2 Credits
Introduction to receptors and intracellular signaling. Agonist and Antagonist
Receptor Interactions, Ion Channels, Tolerance and Intercellular Messenger,
Protein purification, gene therapy and relationship to diseases.
30h (T), C; PR: PCL 301.
PCL 503 Veterinary Pharmacology            2 Credits 
Definition of Veterinary Pharmacology,  Compounding  and  dispensing of
medicines to animals. Compliance of animals with medications Poisons in animal,
Drug s used in the treatment of sheep and goat diseases, poultry diseases, swine
diseases,  small animal (dog  and cat) diseases.  Antimicrobial agents used in
treating animal infections.
30h (T); C, PR: PCL 301.
PHP 599 Projects.                 4 Credits
Each student under the guidance of an approved supervisor is required to conduct
research in an area approved by the Department, culminating in the submission of a
180h (P); C
100 Level
Required Courses : PLB 101 (3), CHM 101 (3), CHM 115 (2), CSC 111 (2),  PHY 191 (1),
PHY 115 (2), PHY 125 (3), GNS 111 (2), PLB 108 (3), ZLY 106 (2), CHM 112 (2), CHM 132
(2), PHY 142 (2), PHY 152 (3), PHY 192 (1), GNS 112 (2), STA 121 (2), STA 124 (2)
= 39 Credits
Compulsory Course: PCP 101 (1)  = 1 Credit
Total = 40 Credits
200 Level
Compulsory Courses: PCG 201 (3), 202 (3),  PCH 201 (1), 202 (3), 203 (2),  204 (2), 205 (2),
206 (2), 207 (2),  PCT 201 (1), PCT 202 (1),  204 (2), 206 (1), PMB 201 (3), PMB 202 (3), PCL
201 (2), 202 (2), 203 (3), 204 (2), GNS 211 (2), GNS 212 (2).
Total = 44 Credits.
DE: PCP 101 (1), GNS 112 (2), GNS 111 (2)= 5 Credits
300 Level
Compulsory Courses:
PCP 301 (2), 302 (1),   304 (1) 306 (1),   PCH 301 (2), 302 (3), 303 (2), PCT 301 (2), 302 (2),
303 (1),  314 (1),  PMB 301 (2), 312 (1), 303 (2), 314 (3), PCG 301 (2),  302 (2), 304 (2), PCL
301 (2), 302 (2),  303 (2),  PCL 304 (2).
= 40 Credits
Required Courses: GNS 311 (2), GSE 301 (3).          = 5 Credits
Total Credits = 45 Credits
400 Level
Compulsory Course:
PCP 401 (2), 402 (2), 403 (1),  404 (2), 405 (2),   406 (2), PCH 401 (3), 402 (2), 403 (2),  PMB
411 (1), 412 (3),  403 (1), 414 (2),  PCT 411 (1), 402 (3),   403 (1), 404 (1),   PCG 401 (3), 402
(3),  PCL 401 (3), 402 (1),  403 (2),  404 (2), 405 (1)
Total Credits = 46 Credits
500 Level
Compulsory Courses:
PCP 501 (2), 502 (2),  503 (2), 504 (2),  505 (2),  506 (4),  PCH 501 (2), 502 (1), 503 (2), 504
(1), PMB 501 (3), 502 (1), PCG 501 (3), 502 (3), PCT 501 (2), 502 (2),  503 (1), PCL 501 (3),
502 (2),  503 (2),  PHP 599 (4)
Total Credits = 46 Credits
Graduation Requirements
UTME=221 Credits
DE=186 Credits
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